A number of energy releases at by-product carbon dioxide plants have been attributed to the presence of high levels of hydrogen, hydrocarbons and/or oxygen in the carbon dioxide plant feed. This publication replaces CGA SA-10, and alerts carbon dioxide producers to potential risks related to changing carbon dioxide feed gas composition. The publication also discusses the dangers related to excess oxygen or hydrocarbon levels in catalytic oxidation and sulfur and hydrocarbon removal systems used to purify carbon dioxide. In addition, it reviews potential fire hazards that can be encountered when spent adsorbent media is exposed to air during periodic replacement are reviewed. Finally, G-6.10 provides recommendations to prevent fire and explosions related to these causes in byproduct carbon dioxide plants.